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Synthesized from the 5-carbon precursors isopentenyl diphosphate and dimethylallyl diphosphate; includes the carotenoids, which are precursors of vitamin A and also possess antioxidant effects.
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KLA seq acetate is a cell membrane-penetrating α-helical amphipathic model peptide. It conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells and covalently links targeted mRNA and fluorescein to form a delivery system with low re-export and less resistance to serum effects.
Cell membrane-penetrating α-helical amphipathic model peptide.
Conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells.
Forms a delivery system for targeted mRNA and fluorescein.
Exhibits low re-export and less susceptibility to serum effects.
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Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol which translocates to the nucleus after binding vitamin D3 thereby coordinating cellular activities VDR forms a heterodimer with RXR binds to DNA response elements and initiates the transcription of vitamin D3-responsive genes Vitamin D Receptor/VDR Protein Mouse (sf9 His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-His labeled tag
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Linaclotide acetate is a potent and selective guanylate cyclase C agonist, developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. This product is for research use only.
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Histrelin acetate is a GnRH analogue and a GnRH Receptor agonist. It works by increasing serum luteinising hormone (LH), follicle stimulating hormone (FSH), and testosterone levels. It is used in the research of prostate cancer and endometriosis.
Stimulates the release of vasopressin (VP) from isolated rat hypothalamo-neurohypophysial explants
Stimulates oxytocin (OT) release from the rat hypothalamo-neurohypophysial system
Rescues circulating LH concentrations in Csfmop/Csfmop mice
Reduces the number of endometrial glands and atrophies the stroma in rabbits
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nor-NOHA (acetate) (CAS 1140844-63-8) is a potent reversible inhibitor of rat liver arginase (Ki 0 5 M) By competitively inhibiting arginase nor-NOHA modulates the cellular balance between the L-arginine-dependent pathways of nitric oxide synthase (NOS) and arginase affecting nitric oxide production and urea cycle metabolism In vitro studies have shown that nor-NOHA suppresses proliferation migration and invasion of HepG2 hepatocellular carcinoma cells induces apoptosis and alters expression of Arg1 MMP-2 P53 and ECD In vivo nor-NOHA improves endothelial function in rat models of inflammation by enhancing NOS activity increasing EDHF and reducing superoxide anion production This compound is widely used to investigate arginase-related mechanisms in cellular and vascular biology
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An analog of 1,24-dihydroxy vitamin D3 which, when used in a 4 μg/g ointment, suppresses psoriasis; inhibits the growth of both normal and psoriatic human keratinocytes (IC50 ~ 10 nM) via the vitamin D receptor; suppresses the production of RANTES and IL-8 by human dermal fibroblasts
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MW 254.24 Da, Purity >99%. Antioxidant flavonoid. Anti-inflammatory and antioxidant properties, also able to induce apoptosis. Potent inhibitor of hypoxia-inducible factor 1α (HIF-1α).
Vitamin A Acetate (Retinyl Retinol) is a group of unsaturated nutritional hydrocarbons that includes retinol retinal retinoic acid and several provitamin A carotenoids among which beta-carotene is the most important
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