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Synthesized from the 5-carbon precursors isopentenyl diphosphate and dimethylallyl diphosphate; includes the carotenoids, which are precursors of vitamin A and also possess antioxidant effects.
Also available in 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants. Purity 98.4%
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An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
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Medchemexpress, HY-N0818 5mg Chikusetsusaponin Iva CAS:51415-02-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Forskolin is a labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory and adenylate cyclase activating properties. 66575-29-9. MFCD00082317
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Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines
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A derivative of betulin; active against E. aerogenes, E. coli, E. faecalis, P. aeruginosa, S. aureus, and C. albicans, as well as L. donovani amastigotes, at 50 µM; is cytotoxic to Huh7 hepatocellular carcinoma cells at 50 µM
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Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources exhibiting pharmacological properties relevant to oncology and infectious diseases research It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling Additionally betulinic acid functions as an agonist for the bile acid receptor TGR5 demonstrating activity with an EC50 of approximately 1 04 M Due to its apoptotic effects and antiviral properties betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies
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MF: C22H34O7, MW: 410.5, ≥99%, Appearance: White to off-white solid. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator.
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Oleanolic aldehyde is an antimicrobial compound effective against oral bacteria like *Streptococcus mutans* and *Porphyromonas gingivalis*, which are implicated in dental caries and periodontal disease. This compound, classified as a triterpene, is naturally derived from plants such as *Vitis vinifera* cv. Zalema.